RainDance Technologies Powers Autism Screening Panel Launched by Greenwood Genetic Center
Panel uses next-generation DNA sequencing to interrogate 62 genes that contain mutations known to be associated with Autism Spectrum Disorders
LEXINGTON, Mass. & CHARLOTTE, N.C., Mar 28, 2012 -- RainDance Technologies, Inc., the Digital Biology™ Company, today announced that Greenwood Genetic Center has commercially launched its Syndromic Autism 62-Gene Panel which was built for use on RainDance’s picodroplet-based targeted sequencing platform. The panel sequences 62 individual autosomal and X-linked genes that represent the most common single gene etiologies associated with Autism Spectrum Disorders (ASD) and syndromes that include autism as a significant phenotypic feature.
“As a condition that is commonly diagnosed, it is essential that families affected by autism have access to resources that help them understand this critical healthcare challenge,” said Julie Jones, PhD, FACMG, Director, Molecular Diagnostic Laboratory at Greenwood Genetic Center. “The simultaneous testing of these genes in a single study provides a significant time and cost advantage over traditional single gene sequencing. Our hope is that this panel enables the more routine use of next-generation sequencing as a tool for identifying the molecular basis of disorders that involve autism.”
The Greenwood Genetic Center panel is based on RainDance’s ASDSeq™ Research Screening Panel, which also targets 62 autosomal and X-linked genes that are known for their clinical association with autism. The ASDSeq panel interrogates all of the exons for each gene, and 1 Kb of the 5-prime promoter region and 3-prime untranslated region (UTR), as well as 50 bases upstream and downstream of each exon to capture intron/exon splice junctions.
“Greenwood is on the leading edge of advancing the field of medical genetics and caring for families impacted by genetic disease and birth defects,” said Andy Watson, Chief Marketing Officer at RainDance Technologies. “This new panel is an excellent example of how RainDance is collaborating with leading scientific institutions to bring powerful genetic research solutions to projects that will expand our understanding of complex conditions like Autism Spectrum Disorders.”
2012 ACMG Annual Clinical Genetics Meeting
Dr. Julie Jones will discuss the 62-Gene Autism Panel at the ACMG meeting in the RainDance Customer Workshop on Friday, March 30 from 12:25 -- 12:55pm ET.
RainDance will be highlighting its complete line of picodroplet-based targeted sequencing solutions including the new ThunderStorm™ System in Booth #517. Additionally, the company’s products will be discussed in a number of customer presentations and posters. For more information, please visit: www.RainDanceTech.com/ACMG .
For more information about Greenwood Genetic Center and the new Syndromic Autism 62-Gene Panel, please visit www.GGC.org . For more information about RainDance, please visit www.RainDanceTech.com or follow us on Twitter at @RainDanceTech.
About RainDance Technologies
RainDance Technologies, the Digital Biology™ Company, is pioneering the use of high-throughput picodroplet-based analysis in human health and life science research. The company's core RainStorm™ technology generates millions of discrete droplets that can encapsulate a single molecule, cell or reaction and be digitally analyzed and sorted one at a time. The power, precision and simplicity of picodroplets enable researchers to answer complex questions with unprecedented sensitivity and quantitation. The complete RainDance solution includes automated instrumentation, customizable bioinformatics and high-value consumables and reagents for applications including targeted next-generation DNA sequencing, methylation, digital PCR and single cell analysis. Based in Lexington, Massachusetts, the company supports scientists around the world through its international sales and support operations and a global network of distributors and service providers. For more information, please visit www.RainDanceTech.com .
For research use only. Not for use in diagnostic procedures.
RainDance Technologies, the RainDance Technologies logo, Digital Biology, ThunderStorm, RainStorm, and ASDSeq are trademarks of RainDance Technologies, Inc. All other brands may be trademarks of their respective holders.